Lizzie

lizzie is mutant American crocodile and the main antagonist of the 2018 film, rampage. he is loosely based on the character of the same name from Midway's Rampage video games. he is George's arch-nemesis.

Description
Once a regular American crocodile from the Florida Everglades, after his mutation, Lizzie grew to gigantic proportions, measuring well over a hundred feet in length. he also developed a forest of razor-sharp blade-like protrusions from his back, a set of vicious tusks, and a spiny club on his tail similar to that of an Ankylosaurus'.

It should be noted that Lizzie was far larger than the other two animals infected by the formula, possibly due to the fact that he consumed the entire canister, whereas the others instead inhaled the gas emitting form the canister before backing off. he is seen to have been driven mad by the formula and wants revenge by enslaving the company who made the serum and destroy every last human in Chicago for their ambition to dominate "his" swamps.

History
After consuming a canister filled with a serum designed to rewrite the genetic coding of its users, Lizzie was transformed into the huge monster described above. When the serum’s creators, a company named Energyne, activated an infrasonic beacon whose purpose was to lure Lizzie and the other two creatures affected by their agent - an albino gorilla named George, and Ralph, a mutated grey wolf - to Chicago, Lizzie quickly made his way to the city and proceeded to wreak havoc, aided by ralph, his former henchman.

However, after George’s former handler, a man named Davis Okoye, managed to steal an antidote which would counteract the properties which made the creatures so aggressive and feed it to George, the pair battled the other two monsters. Okoye was able to trick Ralph into flying into Lizzie’s jaws, but lizzie dodged. George convinced ralph that lizzie was the threat, and ralph betrayed lizzie. ralph attacked lizzie, where the reptile made short work of the smaller beast. Lizzie then fought with George, until Davis started to shoot at Lizzie. This made him furious and was about to kill Davis. This did not happen however, as George stabbed a spear into his eye, killing him. upon his death, Davis, ralph and George reconciled and ralph took the antidote and decided to live with George for helping him.

Trivia

 * Lizzie is the only one of the trio to have changed animal species. In the video games, Lizzie was originally a giant lizard, while in the movie, she is a giant crocodile.
 * This was done to avoid too many similarities with Godzilla, who inspired the design of Lizzie.
 * lizzie originally appears as the secondary antagonist of the first half of the film and the main antagonist of the second half.
 * lizzie shares some similar traits with other villains:
 * he takes over Energyne and it's CEO, related to how lord Cutler Beckett joined forces with davy jones and the flying dutchman (also that their voices are similar)
 * he hates humans with a vengeance: shere khan for some unknown reason in the 1967 version, eye burn in 2016 remake. lizzie for mutating him.
 * he claims destroying man would save the world, but Ultron wanted to wipe out man to make a new one, lizzie wanted to because he thought it would solve all his problems.
 * he was driven mad by the loss of something: captain snow was by his arm and leg cut off, Murray was for triton burning his hand, Gojira was by the atomic bomb that burned out his left eye.
 * he was betrayed by his own henchman, similar to emperor palpatine being killed by darth vader.